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Tolerance to the anti-nociceptive and hypothermic effects of morphine are mediated by multiple isoforms of c-Jun N-terminal Kinase

The abuse and overdose of opioid drugs are growing public health problems, globally. While progress has been made towards understanding the mechanisms governing tolerance to opioids, the exact cellular machinery involved remains unclear. However, there is growing evidence to suggest that c-Jun N-ter...

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Detalhes bibliográficos
Publicado no:Neuroreport
Main Authors: Yuill, Matthew B, Zee, Michael L, Marcus, David, Morgan, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808337/
https://ncbi.nlm.nih.gov/pubmed/26914092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000551
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