In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruzi

Arylimidamides (AIAs) have been shown to have considerable biological activity against intracellular pathogens, including Trypanosoma cruzi, which causes Chagas disease. In the present study, the activities of 12 novel bis-AIAs and 2 mono-AIAs against different strains of T. cruzi in vitro and in vi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Guedes-da-Silva, F. H., Batista, D. G. J., Meuser, M. B., Demarque, K. C., Fulco, T. O., Araújo, J. S., Da Silva, P. B., Da Silva, C. F., Patrick, D. A., Bakunova, S. M., Bakunov, S. A., Tidwell, R. R., Oliveira, G. M., Britto, C., Moreira, O. C., Soeiro, M. N. C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808220/
https://ncbi.nlm.nih.gov/pubmed/26856830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01667-15
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