Cellular Effects of Reversed Amidines on Trypanosoma cruzi

Aromatic diamidines represent a class of DNA minor groove-binding ligands that exhibit high levels of antiparasitic activity. Since the chemotherapy for Chagas' disease is still an unsolved problem and previous reports on diamidines and related analogues show that they have high levels of activ...

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Bibliografiske detaljer
Main Authors: Silva, C. F., Meuser, M. B., De Souza, E. M., Meirelles, M. N. L., Stephens, C. E., Som, P., Boykin, D. W., Soeiro, M. N. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151434/
https://ncbi.nlm.nih.gov/pubmed/17698624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00047-07
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