Cellular Effects of Reversed Amidines on Trypanosoma cruzi

Aromatic diamidines represent a class of DNA minor groove-binding ligands that exhibit high levels of antiparasitic activity. Since the chemotherapy for Chagas' disease is still an unsolved problem and previous reports on diamidines and related analogues show that they have high levels of activ...

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Detalhes bibliográficos
Main Authors: Silva, C. F., Meuser, M. B., De Souza, E. M., Meirelles, M. N. L., Stephens, C. E., Som, P., Boykin, D. W., Soeiro, M. N. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151434/
https://ncbi.nlm.nih.gov/pubmed/17698624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00047-07
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