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Amiodarone Inhibits Trypanosoma cruzi Infection and Promotes Cardiac Cell Recovery with Gap Junction and Cytoskeleton Reassembly In Vitro

We present the results of the first detailed study of the antiproliferative and ultrastructural effects of amiodarone on Trypanosoma cruzi, the causative agent of Chagas' disease. Moreover, we report the effects of this compound on the recovery of F-actin fibrils, connexin43, and contractility...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Adesse, Daniel, Meirelles Azzam, Eduardo, de Nazareth L. Meirelles, Maria, Urbina, Julio A., Garzoni, Luciana R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019665/
https://ncbi.nlm.nih.gov/pubmed/21078932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01129-10
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