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Amiodarone Inhibits Trypanosoma cruzi Infection and Promotes Cardiac Cell Recovery with Gap Junction and Cytoskeleton Reassembly In Vitro

We present the results of the first detailed study of the antiproliferative and ultrastructural effects of amiodarone on Trypanosoma cruzi, the causative agent of Chagas' disease. Moreover, we report the effects of this compound on the recovery of F-actin fibrils, connexin43, and contractility...

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Autori principali: Adesse, Daniel, Meirelles Azzam, Eduardo, de Nazareth L. Meirelles, Maria, Urbina, Julio A., Garzoni, Luciana R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019665/
https://ncbi.nlm.nih.gov/pubmed/21078932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01129-10
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