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In Vitro and In Vivo Biological Effects of Novel Arylimidamide Derivatives against Trypanosoma cruzi

Chagas disease (CD), a neglected tropical disease caused by Trypanosoma cruzi, remains a serious public health problem in several Latin American countries. The available chemotherapies for CD have limited efficacy and exhibit undesirable side effects. Aromatic diamidines and arylimidamides (AIAs) ha...

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Détails bibliographiques
Auteurs principaux: Timm, Bruno Lisboa, da Silva, Patrícia Bernadino, Batista, Marcos Meuser, da Silva, Francisca Hildemagna Guedes, da Silva, Cristiane França, Tidwell, Richard R., Patrick, Donald A., Jones, Susan Kilgore, Bakunov, Stanislav A., Bakunova, Svetlana M., Soeiro, Maria de Nazaré C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068584/
https://ncbi.nlm.nih.gov/pubmed/24752263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02353-14
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