Synergistic cooperation between ABT-263 and MEK1/2 inhibitor: effect on apoptosis and proliferation of acute myeloid leukemia cells

In spite of intensive research to improve treatment of acute myeloid leukemia (AML) more than half of all patients continue to develop a refractory disease. Therefore there is need to improve AML treatment. The overexpression of the BCL-2 family anti-apoptotic members, like BCL-2 or BCL-xL has been...

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Vydáno v:Oncotarget
Hlavní autoři: Airiau, Kelly, Prouzet-Mauléon, Valérie, Rousseau, Benoit, Pigneux, Arnaud, Jeanneteau, Marie, Giraudon, Manon, Allou, Kaoutar, Dubus, Pierre, Belloc, Francis, Mahon, François-Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808037/
https://ncbi.nlm.nih.gov/pubmed/26625317
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