Synergistic cooperation between ABT-263 and MEK1/2 inhibitor: effect on apoptosis and proliferation of acute myeloid leukemia cells

In spite of intensive research to improve treatment of acute myeloid leukemia (AML) more than half of all patients continue to develop a refractory disease. Therefore there is need to improve AML treatment. The overexpression of the BCL-2 family anti-apoptotic members, like BCL-2 or BCL-xL has been...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Airiau, Kelly, Prouzet-Mauléon, Valérie, Rousseau, Benoit, Pigneux, Arnaud, Jeanneteau, Marie, Giraudon, Manon, Allou, Kaoutar, Dubus, Pierre, Belloc, Francis, Mahon, François-Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808037/
https://ncbi.nlm.nih.gov/pubmed/26625317
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