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Combination treatments with ABT-263 and an immunotoxin produce synergistic killing of ABT-263-resistant Small Cell Lung Cancer cell lines

Synergistic killing was achieved when Small Cell Lung Cancer (SCLC) cell lines were incubated with ABT-263 and an immunotoxin directed to the transferrin receptor. SCLC lines are variably sensitive to the BH-3 only peptide mimetic, ABT-263. To determine their sensitivity to toxin-based reagents, we...

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Detalhes bibliográficos
Main Authors: Mattoo, Abid R., FitzGerald, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527691/
https://ncbi.nlm.nih.gov/pubmed/22821746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27732
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