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Single Agent and Synergistic Activity of Maritoclax with ABT-263 in Nasopharyngeal Carcinoma (NPC) Cell Lines

The BCL-2 anti-apoptotic proteins are over-expressed in many cancers and hence are attractive therapeutic targets. In this study, we tested the sensitivity of two Nasopharyngeal Carcinoma (NPC) cell lines HK1 and C666-1 to Maritoclax, which is reported to repress anti-apoptotic protein MCL-1 and BH3...

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Detalhes bibliográficos
Publicado no:Trop Life Sci Res
Main Authors: Xiang, Benedict Lian Shi, Kwok-Wai, Lo, Soo-Beng, Alan Khoo, Mohana-Kumaran, Nethia
Formato: Artigo
Idioma:Inglês
Publicado em: Penerbit Universiti Sains Malaysia 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652248/
https://ncbi.nlm.nih.gov/pubmed/33214852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21315/tlsr2020.31.3.1
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