Combining Paclitaxel with ABT-263 Has a Synergistic Effect on Paclitaxel Resistant Prostate Cancer Cells

We assessed the capability of paclitaxel, one of the taxanes, to induce death in two prostate cancer lines, LNCaP and PC3. Paclitaxel drove an apoptotic pathway in LNCaP, but not in PC3 cells, in response to G2/M arrest. An examination of the levels of anti-apoptotic proteins revealed that Bcl-xl wa...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Wang, Chihuei, Huang, Shih-Bo, Yang, Min-Chi, Lin, Yi-Tsen, Chu, I-Hung, Shen, Ya-Ni, Chiu, Yueh-Ho, Hung, Shao-Hung, Kang, Lin, Hong, Yi-Ren, Chen, Chung-Hwan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374961/
https://ncbi.nlm.nih.gov/pubmed/25811469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120913
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