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Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue

Rapamycin extends life span in mice, yet paradoxically causes lipid dysregulation and glucose intolerance through mechanisms that remain incompletely understood. Whole-body energy balance can be influenced by beige/brite adipocytes, which are inducible by cold and other stimuli via β-adrenergic sign...

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Publicat a:Diabetes
Autors principals: Tran, Cassie M., Mukherjee, Sarmistha, Ye, Lan, Frederick, David W., Kissig, Megan, Davis, James G., Lamming, Dudley W., Seale, Patrick, Baur, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806661/
https://ncbi.nlm.nih.gov/pubmed/26858361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0502
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