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Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue

Rapamycin extends life span in mice, yet paradoxically causes lipid dysregulation and glucose intolerance through mechanisms that remain incompletely understood. Whole-body energy balance can be influenced by beige/brite adipocytes, which are inducible by cold and other stimuli via β-adrenergic sign...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Tran, Cassie M., Mukherjee, Sarmistha, Ye, Lan, Frederick, David W., Kissig, Megan, Davis, James G., Lamming, Dudley W., Seale, Patrick, Baur, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806661/
https://ncbi.nlm.nih.gov/pubmed/26858361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0502
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