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Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue

Rapamycin extends life span in mice, yet paradoxically causes lipid dysregulation and glucose intolerance through mechanisms that remain incompletely understood. Whole-body energy balance can be influenced by beige/brite adipocytes, which are inducible by cold and other stimuli via β-adrenergic sign...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Diabetes
Hauptverfasser: Tran, Cassie M., Mukherjee, Sarmistha, Ye, Lan, Frederick, David W., Kissig, Megan, Davis, James G., Lamming, Dudley W., Seale, Patrick, Baur, Joseph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806661/
https://ncbi.nlm.nih.gov/pubmed/26858361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0502
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