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The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation
Ribosome stalling during translation can potentially be harmful, and is surveyed by a conserved quality control pathway that targets the associated mRNA and nascent polypeptide chain (NC). In this pathway, the ribosome-associated quality control (RQC) complex promotes the ubiquitylation and degradat...
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Publié dans: | eLife |
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Auteurs principaux: | , , , , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
eLife Sciences Publications, Ltd
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805532/ https://ncbi.nlm.nih.gov/pubmed/26943317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11794 |
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