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Selective ribosome profiling as a tool to study the interaction of chaperones and targeting factors with nascent polypeptide chains and ribosomes

A plethora of factors is involved in the maturation of newly synthesized proteins, including chaperones, membrane targeting factors, and enzymes. Many factors act cotranslationally through association with ribosome-nascent chain complexes (RNCs), but their target specificities and modes of action re...

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Detalhes bibliográficos
Main Authors: Becker, Annemarie H., Oh, Eugene, Weissman, Jonathan S., Kramer, Günter, Bukau, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001812/
https://ncbi.nlm.nih.gov/pubmed/24136347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2013.133
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