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The nascent polypeptide in the 60S subunit determines the Rqc2-dependency of ribosomal quality control
Ribosome stalling at tandem CGA codons or poly(A) sequences activates quality controls for nascent polypeptides including ribosome-associated quality control (RQC) and no-go mRNA decay (NGD). In RQC pathway, Hel2-dependent uS10 ubiquitination and the RQC-trigger (RQT) complex are essential for subun...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7913769/ https://ncbi.nlm.nih.gov/pubmed/33511411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab005 |
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