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Evolutionary Conserved Positions Define Protein Conformational Diversity
Conformational diversity of the native state plays a central role in modulating protein function. The selection paradigm sustains that different ligands shift the conformational equilibrium through their binding to highest-affinity conformers. Intramolecular vibrational dynamics associated to each c...
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| Izdano u: | PLoS Comput Biol |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805271/ https://ncbi.nlm.nih.gov/pubmed/27008419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004775 |
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