Inhibition of the phospholipase A(2) activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia

Lung injury associated with hyperoxia reflects in part the secondary effects of pulmonary inflammation and the associated production of reactive oxygen species due to activation of NADPH oxidase, type 2 (NOX2). Activation of NOX2 requires the phospholipase A(2) (PLA(2)) activity of peroxiredoxin 6 (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Redox Biol
Prif Awduron: Benipal, Bavneet, Feinstein, Sheldon I., Chatterjee, Shampa, Dodia, Chandra, Fisher, Aron B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803794/
https://ncbi.nlm.nih.gov/pubmed/25637741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.01.011
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