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The Roles of Peroxidase and Phospholipase A(2) Activities of Peroxiredoxin 6 in Protecting Pulmonary Microvascular Endothelial Cells Against Peroxidative Stress

Aims: Peroxiredoxin 6 (Prdx6), a bifunctional enzyme with glutathione peroxidase and phospholipase A(2) (PLA(2)) activities, has been demonstrated as playing a critical role in antioxidant defense of the lung. Our aim was to evaluate the relative role of each activity in Prdx6-mediated protection of...

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Detalhes bibliográficos
Main Authors: Lien, Yu-Chin, Feinstein, Sheldon I., Dodia, Chandra, Fisher, Aron B.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260966/
https://ncbi.nlm.nih.gov/pubmed/22067043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.3950
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