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Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia
Lung injury associated with hyperoxia reflects in part the secondary effects of pulmonary inflammation and the associated production of reactive oxygen species due to activation of NADPH oxidase, type 2 (NOX2). Activation of NOX2 requires the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx...
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Main Authors: | , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Elsevier
2015-04-01
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叢編: | Redox Biology |
主題: | |
在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2213231715000129 |
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