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Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia

Lung injury associated with hyperoxia reflects in part the secondary effects of pulmonary inflammation and the associated production of reactive oxygen species due to activation of NADPH oxidase, type 2 (NOX2). Activation of NOX2 requires the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bavneet Benipal, Sheldon I. Feinstein, Shampa Chatterjee, Chandra Dodia, Aron B. Fisher
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2015-04-01
Cyfres:Redox Biology
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2213231715000129
Tagiau: Ychwanegu Tag
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