Inhibition of the phospholipase A(2) activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia

Lung injury associated with hyperoxia reflects in part the secondary effects of pulmonary inflammation and the associated production of reactive oxygen species due to activation of NADPH oxidase, type 2 (NOX2). Activation of NOX2 requires the phospholipase A(2) (PLA(2)) activity of peroxiredoxin 6 (...

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Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Benipal, Bavneet, Feinstein, Sheldon I., Chatterjee, Shampa, Dodia, Chandra, Fisher, Aron B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803794/
https://ncbi.nlm.nih.gov/pubmed/25637741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.01.011
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