Inhibition of the phospholipase A(2) activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia

Lung injury associated with hyperoxia reflects in part the secondary effects of pulmonary inflammation and the associated production of reactive oxygen species due to activation of NADPH oxidase, type 2 (NOX2). Activation of NOX2 requires the phospholipase A(2) (PLA(2)) activity of peroxiredoxin 6 (...

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Detaylı Bibliyografya
Yayımlandı:Redox Biol
Asıl Yazarlar: Benipal, Bavneet, Feinstein, Sheldon I., Chatterjee, Shampa, Dodia, Chandra, Fisher, Aron B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2015
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803794/
https://ncbi.nlm.nih.gov/pubmed/25637741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.01.011
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