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Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis

Elevated β-amyloid and impaired synaptic function in hippocampus are among the earliest manifestations of Alzheimer’s disease (AD). Most cognitive assessments employed in both humans and animal models, however, are insensitive to this early disease pathology. One critical aspect of hippocampal funct...

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Dades bibliogràfiques
Publicat a:Hippocampus
Autors principals: Montgomery, Karienn S., Edwards, George, Levites, Yona, Kumar, Ashok, Myers, Catherine E., Gluck, Mark A., Setlow, Barry, Bizon, Jennifer L.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803574/
https://ncbi.nlm.nih.gov/pubmed/26418152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22535
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