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Persistent deficits in hippocampal synaptic plasticity accompany losses of hippocampus-dependent memory in a rodent model of psychosis

Irreversible N-methyl-D-aspartate receptor (NMDAR) antagonism is known to provoke symptoms of psychosis and schizophrenia in healthy humans. NMDAR hypofunction is believed to play a central role in the pathophysiology of both disorders and in an animal model of psychosis, that is based on irreversib...

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Detalhes bibliográficos
Main Authors: Wiescholleck, Valentina, Manahan-Vaughan, Denise
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597980/
https://ncbi.nlm.nih.gov/pubmed/23508474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnint.2013.00012
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