A carregar...

PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis

Inhibition of phosphodiesterase type 4 (PDE4) by rolipram (4-(3-(cyclopentyloxy)-4-methoxyphenyl)-pyrrolidin-2-one) has been the focus of many behavioral and molecular studies in the recent years. Rolipram exhibits memory-enhancing effects in rodents. In vitro studies have shown that long-term poten...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wiescholleck, V, Manahan-Vaughan, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309535/
https://ncbi.nlm.nih.gov/pubmed/22832854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.17
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!