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The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion

BACKGROUND: The promyelocytic leukemia (PML) protein, a type I interferon (IFN-I)-induced gene product and a member of the tripartite motif (TRIM) family, modulates the transcriptional activity of viruses belonging to various families. Whether PML has an impact on the replication of HIV-1 has not be...

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Publicado en:Retrovirology
Main Authors: Masroori, Nasser, Merindol, Natacha, Berthoux, Lionel
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802722/
https://ncbi.nlm.nih.gov/pubmed/27000403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0253-1
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