Disruption of Human TRIM5α Antiviral Activity by Nonhuman Primate Orthologues

TRIM5 is a determinant of species-specific differences in susceptibility to infection by retroviruses bearing particular capsids. Human immunodeficiency virus type 1 (HIV-1) infection is blocked by the alpha isoform of macaque TRIM5 (TRIM5α(rh)) or by the product of the owl monkey TRIM5-cyclophilin...

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Detalhes bibliográficos
Main Authors: Berthoux, Lionel, Sebastian, Sarah, Sayah, David M., Luban, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143641/
https://ncbi.nlm.nih.gov/pubmed/15919943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.12.7883-7888.2005
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