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Disruption of Human TRIM5α Antiviral Activity by Nonhuman Primate Orthologues
TRIM5 is a determinant of species-specific differences in susceptibility to infection by retroviruses bearing particular capsids. Human immunodeficiency virus type 1 (HIV-1) infection is blocked by the alpha isoform of macaque TRIM5 (TRIM5α(rh)) or by the product of the owl monkey TRIM5-cyclophilin...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1143641/ https://ncbi.nlm.nih.gov/pubmed/15919943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.12.7883-7888.2005 |
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