β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia

BACKGROUND: Perturbed balance between NO and O(2) (•−). (ie, NO/redox imbalance) is central in the pathobiology of diabetes‐induced vascular dysfunction. We examined whether stimulation of β(3) adrenergic receptors (β(3) ARs), coupled to endothelial nitric oxide synthase (eNOS) activation, would re‐...

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Bibliographic Details
Published in:J Am Heart Assoc
Main Authors: Karimi Galougahi, Keyvan, Liu, Chia‐Chi, Garcia, Alvaro, Gentile, Carmine, Fry, Natasha A., Hamilton, Elisha J., Hawkins, Clare L., Figtree, Gemma A.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802476/
https://ncbi.nlm.nih.gov/pubmed/26896479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002824
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