β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia

BACKGROUND: Perturbed balance between NO and O(2) (•−). (ie, NO/redox imbalance) is central in the pathobiology of diabetes‐induced vascular dysfunction. We examined whether stimulation of β(3) adrenergic receptors (β(3) ARs), coupled to endothelial nitric oxide synthase (eNOS) activation, would re‐...

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Publicat a:J Am Heart Assoc
Autors principals: Karimi Galougahi, Keyvan, Liu, Chia‐Chi, Garcia, Alvaro, Gentile, Carmine, Fry, Natasha A., Hamilton, Elisha J., Hawkins, Clare L., Figtree, Gemma A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802476/
https://ncbi.nlm.nih.gov/pubmed/26896479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002824
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