β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia

BACKGROUND: Perturbed balance between NO and O(2) (•−). (ie, NO/redox imbalance) is central in the pathobiology of diabetes‐induced vascular dysfunction. We examined whether stimulation of β(3) adrenergic receptors (β(3) ARs), coupled to endothelial nitric oxide synthase (eNOS) activation, would re‐...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Karimi Galougahi, Keyvan, Liu, Chia‐Chi, Garcia, Alvaro, Gentile, Carmine, Fry, Natasha A., Hamilton, Elisha J., Hawkins, Clare L., Figtree, Gemma A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802476/
https://ncbi.nlm.nih.gov/pubmed/26896479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002824
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