Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches

Dynamic interactions between RhoA and Rac1, members of the Rho small GTPase family, play a vital role in the control of cell migration. Using predictive mathematical modeling, mass spectrometry-based quantitation of network components, and experimental validation in MDA-MB-231 mesenchymal breast can...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Syst
Egile Nagusiak: Byrne, Kate M., Monsefi, Naser, Dawson, John C., Degasperi, Andrea, Bukowski-Wills, Jimi-Carlo, Volinsky, Natalia, Dobrzyński, Maciej, Birtwistle, Marc R., Tsyganov, Mikhail A., Kiyatkin, Anatoly, Kida, Katarzyna, Finch, Andrew J., Carragher, Neil O., Kolch, Walter, Nguyen, Lan K., von Kriegsheim, Alex, Kholodenko, Boris N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802415/
https://ncbi.nlm.nih.gov/pubmed/27136688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.01.003
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