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Neutralization of pro‐inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis
Monocytes have emerged as critical driving force of acute inflammation. Here, we show that inhibition of Toll‐like receptor 2(TLR2) dimerization by a TLR2 transmembrane peptide (TLR2‐p) ameliorated DSS‐induced colitis by interfering specifically with the activation of Ly6C(+) monocytes without affec...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801944/ https://ncbi.nlm.nih.gov/pubmed/26884587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592649 |
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