D-Alanylation of Lipoteichoic Acids Confers Resistance to Cationic Peptides in Group B Streptococcus by Increasing the Cell Wall Density

Cationic antimicrobial peptides (CAMPs) serve as the first line of defense of the innate immune system against invading microbial pathogens. Gram-positive bacteria can resist CAMPs by modifying their anionic teichoic acids (TAs) with D-alanine, but the exact mechanism of resistance is not fully unde...

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Autors principals: Saar-Dover, Ron, Bitler, Arkadi, Nezer, Ravit, Shmuel-Galia, Liraz, Firon, Arnaud, Shimoni, Eyal, Trieu-Cuot, Patrick, Shai, Yechiel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435245/
https://ncbi.nlm.nih.gov/pubmed/22969424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002891
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