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Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases

Endotoxin tolerance protects the host by limiting excessive 'cytokine storm' during sepsis, but compromises the ability to counteract infections in septic shock survivors. It reprograms Toll-like receptor (TLR) 4 responses by attenuating the expression of proinflammatory cytokines without...

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Bibliografische gegevens
Gepubliceerd in:J Innate Immun
Hoofdauteurs: Xiong, Yanbao, Murphy, Michael, Manavalan, Tissa T., Pattabiraman, Goutham, Qiu, Fu, Chang, Hui-Hsin, Ho, I-Cheng, Medvedev, Andrei E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801746/
https://ncbi.nlm.nih.gov/pubmed/26457672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000440838
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