Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling

Development of endotoxin tolerance in macrophages during sepsis reprograms Toll-like receptor 4 signaling to inhibit proinflammatory cytokines without suppressing anti-inflammatory and antimicrobial mediators and protects the host from excessive inflammation and tissue damage. However, endotoxin tol...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Leukoc Biol
Hlavní autoři: Murphy, Michael B., Xiong, Yanbao, Pattabiraman, Goutham, Manavalan, Tissa T., Qiu, Fu, Medvedev, Andrei E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2015
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661042/
https://ncbi.nlm.nih.gov/pubmed/26310831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2VMA0515-229RR
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky