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Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases

Endotoxin tolerance protects the host by limiting excessive 'cytokine storm' during sepsis, but compromises the ability to counteract infections in septic shock survivors. It reprograms Toll-like receptor (TLR) 4 responses by attenuating the expression of proinflammatory cytokines without...

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Détails bibliographiques
Publié dans:J Innate Immun
Auteurs principaux: Xiong, Yanbao, Murphy, Michael, Manavalan, Tissa T., Pattabiraman, Goutham, Qiu, Fu, Chang, Hui-Hsin, Ho, I-Cheng, Medvedev, Andrei E.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801746/
https://ncbi.nlm.nih.gov/pubmed/26457672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000440838
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