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Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases

Endotoxin tolerance protects the host by limiting excessive 'cytokine storm' during sepsis, but compromises the ability to counteract infections in septic shock survivors. It reprograms Toll-like receptor (TLR) 4 responses by attenuating the expression of proinflammatory cytokines without...

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Detalles Bibliográficos
Publicado en:J Innate Immun
Main Authors: Xiong, Yanbao, Murphy, Michael, Manavalan, Tissa T., Pattabiraman, Goutham, Qiu, Fu, Chang, Hui-Hsin, Ho, I-Cheng, Medvedev, Andrei E.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801746/
https://ncbi.nlm.nih.gov/pubmed/26457672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000440838
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