Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20

Lignende værker

• IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance
  af: Xiong, Yanbao, et al.
  Udgivet: (2013)
• Endotoxin Tolerance Impairs IL-1 Receptor-Associated Kinase (IRAK) 4 and TGF-β-activated Kinase 1 Activation, K63-linked Polyubiquitination and Assembly of IRAK1, TNF Receptor-associated Factor 6, and IκB Kinase γ and Increases A20 Expression
  af: Xiong, Yanbao, et al.
  Udgivet: (2011)
• Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance
  af: Murphy, Michael, et al.
  Udgivet: (2015)
• Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-β-dependent pathways and increases expression of negative regulators of TLR signaling
  af: Piao, Wenji, et al.
  Udgivet: (2009)
• Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling
  af: Murphy, Michael B., et al.
  Udgivet: (2015)