Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-β-dependent pathways and increases expression of negative regulators of TLR signaling

Endotoxin tolerance reprograms cell responses to LPS by repressing expression of proinflammatory cytokines, while not inhibiting production of anti-inflammatory cytokines and antimicrobial effectors. Molecular mechanisms of induction and maintenance of endotoxin tolerance are incompletely understood...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Piao, Wenji, Song, Chang, Chen, Haiyan, Quevedo Diaz, Marco A., Wahl, Larry M., Fitzgerald, Katherine A., Li, Liwu, Medvedev, Andrei E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Society for Leukocyte Biology 2009
Materias:
Receptors, Signal Transduction, & Genes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796624/
https://ncbi.nlm.nih.gov/pubmed/19656901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0309189
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares