TLR4/MyD88/PI3K interactions regulate TLR4 signaling

TLRs activate immune responses by sensing microbial structures such as bacterial LPS, viral RNA, and endogenous “danger” molecules released by damaged host cells. MyD88 is an adapter protein that mediates signal transduction for most TLRs and leads to activation of NF-κB and MAPKs and production of...

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Detaylı Bibliyografya
Asıl Yazarlar: Laird, Michelle H. W., Rhee, Sang Hoon, Perkins, Darren J., Medvedev, Andrei E., Piao, Wenji, Fenton, Matthew J., Vogel, Stefanie N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Society for Leukocyte Biology 2009
Konular:
Receptors, Signal Transduction, and Genes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698589/
https://ncbi.nlm.nih.gov/pubmed/19289601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1208763
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