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TLR4/MyD88/PI3K interactions regulate TLR4 signaling
TLRs activate immune responses by sensing microbial structures such as bacterial LPS, viral RNA, and endogenous “danger” molecules released by damaged host cells. MyD88 is an adapter protein that mediates signal transduction for most TLRs and leads to activation of NF-κB and MAPKs and production of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Society for Leukocyte Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698589/ https://ncbi.nlm.nih.gov/pubmed/19289601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1208763 |
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