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Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling
Development of endotoxin tolerance in macrophages during sepsis reprograms Toll-like receptor 4 signaling to inhibit proinflammatory cytokines without suppressing anti-inflammatory and antimicrobial mediators and protects the host from excessive inflammation and tissue damage. However, endotoxin tol...
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| Publicado no: | J Leukoc Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4661042/ https://ncbi.nlm.nih.gov/pubmed/26310831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2VMA0515-229RR |
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