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Sterol hindrance of Orai activation
Orai channels at the plasma membrane mediate store-operated Ca(2+) entry in response to Ca(2+) depletion of the endoplasmic reticulum. Orai channels are gated by stromal-interacting molecule proteins, which act as Ca(2+) sensors, and the association of these proteins is enhanced in cholesterol-rich...
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| Gepubliceerd in: | Sci Signal |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801107/ https://ncbi.nlm.nih.gov/pubmed/26956482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf2357 |
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