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The Critical Role of STIM1-Dependent Ca(2+) Signalling during T-cell Development and Activation

T lymphocytes are key cellular effectors of adaptive immunity able to recognize a virtually limitless number of antigenic peptides and mount an immune response. Ca(2+) signals are crucial to the development and activation of T cells and Stromal Interaction Molecule 1 (STIM1) has been identified as a...

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Autors principals: Samakai, Elsie, Hooper, Robert, Soboloff, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797843/
https://ncbi.nlm.nih.gov/pubmed/23906672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2013.07.014
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