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STIM1 is required for attenuation of PMCA-mediated Ca(2+) clearance during T-cell activation
T-cell activation involves a complex signalling cascade uniquely dependent on elevated cytosolic Ca(2+) levels. Further, the spatiotemporal characteristics of this Ca(2+) signal play a critical role in this process via selective activation of transcription factors. In T cells, store-operated Ca(2+)...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298001/ https://ncbi.nlm.nih.gov/pubmed/22246182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.495 |
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