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Quillaja saponin variants with central glycosidic linkage modifications exhibit distinct conformations and adjuvant activities
Immunological adjuvants such as the saponin natural product QS-21 help stimulate the immune response to co-administered antigens and have become increasingly important in the development of prophylactic and therapeutic vaccines. However, clinical use of QS-21 is encumbered by chemical instability, d...
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| Publicat a: | Chem Sci |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800320/ https://ncbi.nlm.nih.gov/pubmed/27014435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02978c |
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