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Quillaja saponin variants with central glycosidic linkage modifications exhibit distinct conformations and adjuvant activities
Immunological adjuvants such as the saponin natural product QS-21 help stimulate the immune response to co-administered antigens and have become increasingly important in the development of prophylactic and therapeutic vaccines. However, clinical use of QS-21 is encumbered by chemical instability, d...
Shranjeno v:
| izdano v: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Royal Society of Chemistry
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800320/ https://ncbi.nlm.nih.gov/pubmed/27014435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02978c |
| Oznake: |
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