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Paracetamol decreases steady‐state exposure to lamotrigine by induction of glucuronidation in healthy subjects
AIM: Patients receiving lamotrigine therapy frequently use paracetamol concomitantly. While one study suggests a possible, clinically relevant drug–drug interaction, practical recommendations of the concomitant use are inconsistent. We performed a systematic pharmacokinetic study in healthy voluntee...
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| Publicado en: | Br J Clin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4799936/ https://ncbi.nlm.nih.gov/pubmed/26588196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12840 |
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