The effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite: paracetamol glucuronide

The study aimed to examine the effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite, paracetamol glucuronide. Both drugs share metabolic pathways in the liver, and the drug interactions between sunitinib and paracetamol administered in higher doses were repo...

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Dades bibliogràfiques
Publicat a:Eur J Drug Metab Pharmacokinet
Autors principals: Karbownik, Agnieszka, Szałek, Edyta, Sobańska, Katarzyna, Połom, Wojciech, Grabowski, Tomasz, Biczysko-Murawa, Anna, Matuszewski, Marcin, Wolc, Anna, Grześkowiak, Edmund
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2014
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426134/
https://ncbi.nlm.nih.gov/pubmed/24676873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-014-0191-z
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