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The effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite: paracetamol glucuronide

The study aimed to examine the effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite, paracetamol glucuronide. Both drugs share metabolic pathways in the liver, and the drug interactions between sunitinib and paracetamol administered in higher doses were repo...

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Detalhes bibliográficos
Publicado no:Eur J Drug Metab Pharmacokinet
Main Authors: Karbownik, Agnieszka, Szałek, Edyta, Sobańska, Katarzyna, Połom, Wojciech, Grabowski, Tomasz, Biczysko-Murawa, Anna, Matuszewski, Marcin, Wolc, Anna, Grześkowiak, Edmund
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426134/
https://ncbi.nlm.nih.gov/pubmed/24676873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-014-0191-z
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