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Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors
AIMS: We aimed to investigate the effects of tyrosine kinase inhibitors (TKIs) on paracetamol (acetaminophen) glucuronidation. METHODS: The inhibition of nine small molecule TKIs on paracetamol glucuronidation was investigated in human liver microsomes (HLMs) and recombinant human UDP-glucuronosyltr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099378/ https://ncbi.nlm.nih.gov/pubmed/21235620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.03911.x |
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